Jarrow Fem-Dophilus, 60 Cap

What does Fem-Dophilus® do?

Fem-dophilus® contains two patented and clinically documented probiotic strains, Lactobacillus rhamnosus GR-1® and Lactobacillus reuteri RC-14®, discoveredand developed by Dr. Gregor Reid and Dr. Andrew Bruce at Urex Biotech. Over 20 years of research supports the oral use of GR-1® and RC-14® to colonize and protect the vaginal tract.*Clinical trials have shown that GR-1® and RC-14®:

• Help to maintain or restore healthy vaginal flora that are important in  maintaining vaginal health*

• Support the health of the urinary tract*

Fem-dophilus® is manufactured under pharmaceutical GMP conditions with guaranteed potency and consistency. The probiotic strains in Fem-dophilus® are in a proprietary polysaccharide matrix, which protects the bacteria from stomach acid and enhances probiotic bacteria survival to the lower intestine.*

Prevention Magazines Top Medical Breakthroughs of 2007

Probiotics--friendly bacteria that thrive in the body--are known to prevent or even cure yeast infections and bacterial vaginosis. Now there's an OTC supplement containing the two Lactobacillus strains documented to promote vaginal health. The probiotic pill Fem-Dophilus has erased up to 90% of vaginal bacterial infections and significantly reduced yeast growth in trials by coating the lining of vaginal tissues and producing acids that keep pathogens from gaining a foothold. When women take antibiotics, Fem-Dophilus doubles the drugs' effectiveness by recolonizing the vagina with healthy flora.

Who Can Benefit From this Product?

Fem-Dophilus is a probiotic product for women who wish to maintain internal, especially vaginal, floral balance.* Healthy flora has been documented as a key to vaginal and urinary tract health.

What Distinguishes this Product?

• Patented Probiotic Microorganisms: L. rhamnosus GR-1® and L. reuteri RC-14®
• 20+ Years of Research Support its Benefits
• More than 20 studies demonstrating safety and efficacy*
• Promotes Vaginal Health Naturally*

How Does Each Active Ingredient Functionin this Product?

L. rhamnosus GR-1® & L. reuteri RC-14®:  Promote beneficial microorganisms that populate the vaginal tract and compete against harmful bacteria and yeasts.*

Fem-Dophilus®
Fem-Dophilus® contains two patented and clinically tested strains of probiotic bacteria, Lactobacillus rhamnosus GR-1® and Lactobacillus reuteri RC-14®, discovered and developed by Drs. Gregor Reid and Andrew Bruce of Urex Biotech. Research has confirmed that GR-1 and RC-14 taken as an oral supplement colonize and protect the vaginal tract. Over twenty years of research has shown that GR-1 and RC-14 help to restore and maintain the balance of flora important to vaginal and urinary tract health.*

This patented product is manufactured at a Good Manufacturing Practices (GMP) pharmaceutical facility under strict quality control to ensure potency and consistency. The probiotic strains in Fem-Dophilus are delivered in a proprietary polysaccharide matrix that
protects the bacteria from stomach acid and enhances the survival of these species as they reach the intestinal tract.*

Fem-Dophilus has been recognized as one of the Top 10 Breakthroughs in 2007 by Prevention Magazine in its January 2008 issue, and was the only dietary supplement included on the Top 10 list.

Probiotics Support for Vaginal Health
Purchasers of other Jarrow Formulas® probiotic products are aware of the many health benefits that can be experienced from supplementing with beneficial bacteria, i.e. probiotics. For instance, Jarro-Dophilus EPS® is designed to boost the natural “friendly” bacteria of the gut by supplying beneficial strains that are needed to maintain a healthy intestinal environment. Jarro-Dophilus EPS is a compatible blend of friendly bacteria designed to promote intestinal balance.*

Restoring the balance of microorganisms to the gut both helps to crowd out unwanted organisms and promote proper immune response, as well.* Less well known is the fact that special strains of probiotic bacteria also contribute to vaginal health.*

Women with an unhealthy intestinal microflora profile are at a higher risk of developing urogenital infections. Fortunately, scientific findings indicate that supportive microflora that can colonize the vagina play an important role in maintaining health. This suggests that the daily ingestion of certain probiotics may also provide a natural, safe and effective means of balancing microorganisms in the vaginal tracts.* Clinical research supports the proposition that proper use of oral probiotics can do just this.*

Oral Probiotics Influence Vaginal Floral Balance
Clinical trials have found that oral intake of probiotics can significantly and beneficially affect the balance of vaginal flora.* However, only certain probiotics can provide this benefit. Direct comparisons have demonstrated that the probiotic species and strains must be carefully selected in order to promote vaginal health.

The major criteria required in selecting beneficial probiotics are their ability to colonize the vagina and reduce undesirable vaginal microflora. In one trial, GR-1 and RC-14 administered in skim milk were given orally to 10 women twice daily for 14 days. GR-1 and RC-14 were recovered from the vagina and identified by morphology and molecular typing within 1 week of commencement of the trial. In another randomized, placebo-controlled trial, GR-1 and RC-14 were given to 64 women for 60 days. Microscopy analysis showed the restoration of healthy vaginal flora level in 37% of women taking GR-1 and RC-14 vs. 13% in subjects in placebo group. Other trials have also confirmed the benefits of GR-1 and RC-14 intake.*

In order for a probiotic to be effective, significant numbers of live bacteria (indicated as Colony Forming Units or CFU) must survive when the probiotic is taken by mouth. Tests for the gastrointestinal survivability of strains have shown good results. GR-1 and RC-14 are also bile tolerant and survive passage through the gastrointestinal tract. RC-14 and GR-1 are tolerant to 0.3 and 0.5 percent (w/v) bile, respectively. According to the experts, both strains can therefore be considered both acid and bile tolerant given that a concentration of 0.3 percent is considered physiologically relevant.*

Safety
Several human and in vitro studies have documented the safety of GR-1 and RC-14. Jarrow Formulas obtains the materials for Fem-Dophilus from a pharmaceutical GMP level manufacturer. Advanced and accurate genetic analyses are conducted to ensure the correct identity of the strains. This is the ultimate in quality control.

More than 20 clinical studies spanning 20 years of research have validated the safety and beneficial effects of the probiotic strains Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 that make up Fem-Dophilus.

Size: 60 Caps

Other Ingredients

Dextrose anhydrate, potato starch, microcrystalline cellulose and magnesium stearate (vegetable source). Capsule consists of gelatin and titanium dioxide.

No wheat, no gluten, no soybeans, no egg, no fish/shellfish, no peanuts/tree nuts.

Contains: Dairy (casein, in trace amounts).

Keep out of the reach of children.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.