Jarrow Ashwagandha (Sensoril), 225 mg, 120 Cap

What does Ashwagandha do?

Ashwagandha has been used in the Indian tradition of Ayurveda to improve musculoskeletal function and as a tonic to improve overall health.* Experimental studies demonstrate that Ashwagandha is an antioxidant that supports joint mobility and resistance to fatigue.* Sensoril® is protected by U.S. patent Nos. 6,153,198 and 6,713,092 and is a trademark of Natreon, Inc.

Ashwagandha or Withania somnifera, also known as Ashwagandha, Indian ginseng, Winter cherry, Ajagandha, Kanaje Hindi, Amukkuram in Malayalam and Samm Al Ferakh, is a plant in Solanaceae or nightshade family.

It grows as a stout shrub that reaches a height of 170 cm (5.6 ft). Like the tomato which belongs to the same family, it bears yellow flowers and red fruit, though its fruit is berry-like in size and shape. Ashwagandha grows prolifically in India, Nepal, Pakistan, Sri Lanka and Bangladesh. It is commercially cultivated in Madhya Pradesh (a state in India).

Medicinal Use
In Ayurveda ashwagandha is considered a rasayana herb. This herb is also considered an adaptogen which is an herb that works to normalize physiological function, working on the HPA axis and the neuroendocrine system. In Ayurveda, the fresh roots are sometimes boiled in milk, prior to drying, in order to leach out undesirable constituents. The berries are used as a substitute for rennet, to coagulate milk in cheese making.

Ashwagandha in Sanskrit means "horse's smell," probably originating from the odor of its root which resembles that of sweaty horse. In Tamil language|Tamil, it is called Amukkrang Kilangu and is used in several medicines.

The species name somnifera means "sleep-inducing" in Latin, indicating that to it are attributed sedating properties, but it has been also used for sexual vitality and as an adaptogen. Some herbalists refer to ashwagandha as Indian ginseng, since it is used in ayurvedic medicine in a way similar to that ginseng is used in traditional Chinese medicine.

Seven American and four Japanese firms have filed for grant of patents on formulations containing extracts of the herb Ashwagandha. Fruits, leaves and seeds of the Indian medicinal plant withania somnifera have been traditionally used for the Ayurvedic system as aphrodisiacs, diuretics and for treating memory loss. The Japanese patent applications are related to the use of the herb as a skin ointment and for promoting reproductive fertility. The U.S based company Natreon has also obtained a patent for an Ashwagandha extract.

Another US establishment, the New England Deaconess Hospital, has taken a patent on an Ashwagandha formulation claimed to alleviate symptoms associated with arthritis. The product called "ashwagandha oil" is a combination of ashwagandha with almond oil and rose water designed to be used as a facial toner, and should not be consumed orally.

Active Constituents
The main constituents of ashwagandha are alkaloids and steroidal lactones. Among the various alkaloids, withanine is the main constituent. The other alkaloids are somniferine, somnine, somniferinine, withananine, pseudo-withanine, tropine, pseudo-tropine, cuscohygrine,anferine and anhydrine. Two acyl steryl glucoside viz. sitoindoside VII and sitoindoside VIII have been isolated from root. The leaves contain steroidal lactones, which are commonly called withanolides. The withanolides have C28 steroidal nucleus with C9 side chain, having six membered lactone ring.

Pharmacological effects
Ashwagandha is reported to have anti-carcinogenic effects in animal and cell cultures by decreasing the expression of nuclear factor-kappaB, suppressing intercellular tumor necrosis factor, and potentiating apoptotic signalling in cancerous cell lines.

Sensoril ® Ashwagandha extract
Sensoril, a proprietary, standardized extract of the Ayurvedic botanical, Ashwagandha (Withania somnifera). Sensoril helps shield the body against the negative effects of stress via unique withanolide bioactive compounds that mimic the body’s own stress-reducing hormones.*

The physiological wellness benefits afforded by Sensoril have been substantiated as structure/function health claims and can be applied to many product categories including: Stress, Energy, Mental Cognition, Cardiovascular Function, Glucose Release, and Weight Management.* Sensoril’s efficacy in these claims areas is supported by a randomized, double-blind, placebo controlled human clinical trial.

Sensoril’s ability to balance and harmonize the body’s systems results from its adaptogenic properties.* Adaptogens are a rare group of botanicals and mushrooms possessing unique properties that increase the body’s ability to resist and recover from stress while stimulating an overall feeling of balance and normalization.* With its adaptogenic properties, Sensoril^® is novel in that it provides long-lasting stress relief while improving mood when taken as a tonic on a daily basis, without any negative side effects.*

Sensoril‘s substantiated structure/function claims are in accordance with the requirements of the Dietary Supplement Health and Education Act of 1994 and have been submitted to the Food and Drug Administration. Some examples of the many claims Sensoril^® features include:

· Helps inhibit fatigue, tension and exhaustion from everyday stressors*

· Helps promote mental clarity, concentration and alertness*

· Helps enhance balanced energy levels for physical performance and endurance*

· Supports healthy cardiovascular function*

· Helps support blood sugar levels that are already within the normal range*

Size: 120 Caps

Other Ingredients

Cellulose, magnesium stearate (vegetable source) and silicon dioxide. Capsule consists of hydroxypropylmethylcellulose.

No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

Suitable for vegetarians/vegans

Keep out of the reach of children.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.